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Incidence
Risk Factors
Pathology
Screening and Early Detection
Clinical Evaluation
Staging of Pancreatic Cancer
Treatment
Periampullary Tumors
References
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Healthcare Professionals

Incidence1

  • Pancreatic cancer is considered to be one of the leading causes of cancer deaths in advanced countries and it is on the rise in developing countries like India. A large number of patients with pancreatic cancer receive only palliative therapy because of advanced stage at presentation.
  • Pancreatic cancer is the fifth leading cause of cancer related death in the US with an incidence rate of 9 cases per 100,000 people. Approximately 28,000 to 30,000 cases of pancreatic cancer (ductal adenocarcinoma being the most common form) are diagnosed per year. Men are at a slightly greater risk compared to women.
  • The chances of survival for untreated patients are very poor. Considering the average of all stages of the disease, 1-year survival rate is 19% and the 5-year survival rate is 4%. At the time of diagnosis approximately 80% of all pancreatic cancers are metastatic, leaving complete resection as the choice of treatment for only 20% of patients. The 5-year survival of operated patients approaches 40% when performed at specialised medical institutions.
  • The incidence of pancreatic cancer in India is low (0.5-2.4 per 100,000 men and 0.2-1.8 per 100,000 women). The incidence of pancreatic cancer is higher in the urban male populations of western and northern parts of India but time trends show that this figure is increasing for both carcinoma of the pancreas and also periampullary tumors.
  • The annual pancreatic cancer load of India in 2001 was approximately 14,230 patients: the estimated current figure is approximately 17,000 and is likely to increase in the near future. The situation calls for the need of multicentric studies, more systematic approach to documentation at all levels and the need to identify potentially preventable risk factors associated with pancreatic cancer in India.